Monday, 12th October 18th International Symposium on Dendritic Cells 2026

• Surveillance of intestinal antigens by functionally diverse antigen-presenting cells - Dan Littman
• Thetis cells: Defining the Ontogeny and Function of a Novel APC Lineage - Chrysothemis Brown
• Rethinking Immaturity: Signals Shaping Dendritic Cell Function in Early Life - Barbara Schraml
• Epigenetic Heterogeneity in Dendritic Cell Subsets Underlies Immune Response Variation - Mya Gough
• Thymic myeloid cell heterogeneity reveals a novel population of perivascular transitional dendritic cells with antigen sampling capacity. - Matous Voboril
• Defining the factors governing intratumoral cDC1-CD8 T cell clusters - Maria Parra Reyes

• Pathways of homeostatic dendritic cell maturation - Sophie Janssens
• Environment Patrolling by colonic Dendritic Cells - Ana-Maria Lennon-Dumenil
• Stromal regulation of dendritic cell and macrophage homeostasis - Shannon Turley
• Neuronal control of dendritic cell migration drives sex-biased skin immunity - Konrad Knöpper
• Influence of cancer cell mechanical properties on dendritic cell sentinel function. - Yazmina Quintana Perez
• Macrophage nibbling without killing: a novel endosomal route for CD8 T cell priming - Amy C Fan
• Chemokine-Driven Spatial Niches Regulate Distinct APC-T cell Neighbourhoods within the Human Lymph Node - Marcus Ooi

• Homologous MHC class I/II epitopes program cDC1-like differentiation of monocyte-derived dendritic cells via mTORC1 signaling inhibition   - Sharon Bright Amanya
• Single-nucleus multiomic profiling of human dendritic cells heterogeneity   - Simone Balin
• Pre-Defined Interferon Programs in Hematopoietic Stem Cells Shape Vaccine Responsiveness in Humans - Diego Diaz-Dinamarca
• Transcriptional insights into dendritic cell survival - Signe Holst
• Trim33 is essential for the development and maintenance of plasmacytoid and type 1 conventional dendritic cells - Pei-Feng Hsu
• Deubiquitinase USP22 is Required for Conventional Dendritic Cell 1 (cDC1) Development - Chieh-Yu (Jessie) Lee
• Dual role of Mef2c in promoting pDC development and limiting antiviral responses - Tai-Ling Li
• Clarifying Dendritic cell terminology in the context of single-cell diversity - Sunrito Mitra
• CD16/32b surface expression reflects dendritic cell activation, rather than a stable dendritic cell subset. - Sunrito Mitra
• Temporal analysis of the transcriptional regulation of dendritic cell activation reveals subtype-specific gene regulatory networks and key transcription factors - Ignacio Heras-Murillo
• Decoding the functional heterogeneity of RORγt⁺ dendritic cells - Pin-Yu Kuo
• Revisiting antigen presenting cell lineages in intestinal immunity - Gianfranco L Yee
• Age- and tissue-dependent diversity of human plasmacytoid dendritic cells uncovers a cycling subset dominant in early life and cancer - Alina Ulezko Antonova
• Temporal Dynamics of MxA, ISG15, and CCL5 Expression in Monocyte-Derived Alpha-Type 1 Polarized Dendritic Cells - Guilherme Castellani
• Deletion of Phosphoinositide 3-kinase-γ (PI3Kγ) enhances conventional Dendritic Cell Cross-Presentation of Immune Complexes - Kenneth M Adusei
• Comparative analysis of antigen presentation by APC subsets using a mouse model expressing multiple disease-relevant antigens - Camillo Bechi Genzano
• Efferocytosis and necrophagy are distinct pathways for dead cell uptake and presentation by cDC1s - Victor Bosteels
• Identification of antigen-presenting cell–T cell interactions driving immune responses to luminal antigens - Maria Cecília C. Canesso
• Unravelling the processing pathway for transmembrane proteins in human dendritic cells - Tongxiang Chen
• A point mutation in Interferon Regulatory Factor 4 impairs dendritic cell instruction of T cell fate - Yanran Fan
• Migratory dendritic cells mediate communication between the central nervous system and the peripheral immune system   - Viola Bugada
• Impact of skin fibrosis on dendritic cell function and migration - Vincent Calmettes
• BHLHE40/DEC1 programs epidermal Langerhans Cell identity - Sally Connolly
• Respiratory virus induced changes in pulmonary conventional dendritic cell subsets.  - Maddisen Dwelley
• Bone morphogenetic protein signaling promotes tolerogenic DC differentiation in psoriatic inflammatory lesions and histiocytosis - Sara Gvozden Popovic
• Interplay between dendritic cells and macrophages drives generation of commensal-specific homeostatic intestinal Th17 cells - Junjie Ma
• Mature dendritic cells orchestrate age-associated regulatory lymphoid niches in tissues - Ines Marin
• Dendritic cells, bridging neuromodulation and immunity - MARIA MML MARTINEZ-LOPEZ
• Transcription factor Etv3 controls the positioning of mature dendritic cells within the lymph node - Daniel C Martinez-Krams
• Maternal Antibodies Regulate the Establishment of Oral and Salivary Mucosal Immunity - Reem Naamneh
• Cytoskeletal control of podosome–focal adhesion dynamics in GM-CSF-derived dendritic cells - Adrianna Niedzielska
• Defining the role of human anogenital antigen-presenting cells in HIV transmission - Jake W Rhodes
• Fantastic antigen-presenting cells and where to find them: Microglia-CD8⁺ T cell duos in the aged Alzheimer's brain following peripheral infections - Michael A. LaPorta
• Age-related changes in monocyte-derived DC subset differentiation - Yogesh Sardana
• Dissecting subset-specific activation programmes of skin migratory type 2 dendritic cells - Olivier Lamiable
• Phosphoglycerate dehydrogenase moonlights to shape dendritic cell crosstalk and effector functions     - Ebenezer Asiedu
• Threonine is critical for dendritic cell development and effector functions - Ebenezer Asiedu
• Calcium dynamics in Dendritic cells in response to bacteria - Gaetan Barbet
• AMPK is a metabolic checkpoint for cDC1 identity and function - Pedro P. Cunha
• Metabolic Rewiring of Monocyte Fate for Cancer Immunotherapy - FERNANDO ERRA DIAZ
• Unravelling the role of lung dendritic cell development and immunity through the lens of O-GlcNAcylation - Alexander Harvey
• Short-term high-fat diet feeding disrupts cDC1 homeostasis via reduced lymphocyte-derived FLT3L and induces expansion of Th17 T-cells - Paul Maier
• The solute carrier transporter SLC15A4 promotes anti-viral signaling in dendritic cells - Adriana R Mantegazza
• Role of antigen presenting cells in the changes in immune response to SARS-Cov-2 with advancing age in humans - Anshu AGRAWAL
• Primary infection alters dendritic cell subset ratios and responsiveness to secondary infection - Sophia Agrusa
• Egr2-dependent Mo-DCs regulate immunosuppressive NK cells, promoting neutrophil-mediated protective immunity against acute Listeria infection - Dr. Muhammad Umer Ashraf
• Plasmacytoid dendritic cells initiate local type I interferon responses via contact-dependent recognition of infected macrophages - Annesa Das
• Pro-Inflammatory Response of Human Monocyte-Derived Dendritic Cells to Bacterial Biofilms - Stefania Gallucci
• Single-Cell Characterization of Dendritic Cell Progenitor Adaptations During a Viral Infection - Hector U Gaspar-Eslava
• Upon stimulation by HIV-1 or HIV-2-infected T cells,  pDC diversify into discrete populations with contrasting functions : potential targets for immune therapy - Anne Hosmalin
• RIG-I-like receptor-dependent type I Interferon regulates antigen dose and activation in yellow fever vaccine 17D-infected antigen presenting cells - Anne Krug
• Transcriptional profiling reveals subset-specific cathepsin responses in cDC1 and cDC2 during ectromelia virus infection - Adrianna Niedzielska
• Inhibition of human monocyte-to-dendritic cell differentiation by ESAT-6 protein of Mycobacterium tuberculosis - Rahila Qureshi
• Early cDC2/moDC Activation and Day 7 Divergent Expansion of Extrafollicular Th10 and Regulatory cTfr Cells Distinguish Strong from Weak Influenza Vaccine Responses in Older Adults - Sathyabaarathi Ravichandran
• Short-Chain Fatty Acids Modulate the Response of Murine Macrophages and Dendritic Cells to Paracoccidioides brasiliensis   - ALDO H TAVARES
• Type III IFNs production in type I classical dendritic cells to virus-infected cells - TAEJIN YUN
• SAPS3 Regulates T Cell Exhaustion and Antiviral Immunity during Chronic Viral Infection - Xiyu Chen

• The role of plasmacytoid dendritic cells in anti-viral immunity and in homeostasis - Elena Tomasello
• Using mRNA-LNP technology to manipulate conventional dendritic cell biology - Justine Mintern
• The tumor-sentinel lymph node immuno-migratome reveals CCR7⁺ dendritic cells drive response to sequenced immunoradiotherapy - Robert Saddawi-Konefka
• Fine-Tuned Help: Orchestrating Dendritic Cell-T Cell Crosstalk in Antitumor Immunity - Eynav Klechevsky
• Single-cell spatial transcriptomics of fixed, paraffin-embedded biopsies links dendritic cell-enriched gut-associated lymphoid aggregates to an archetype of vedolizumab non-response - Alexis J Combes
• Revisiting Dendritic Cells in Autoimmunity - Juan Villar Vesga
• Large Scale Production of Human Conventional Type I Dendritic Cells for Cancer Immunotherapy  - Sreekumar Balan

• Connecting DC metabolism and function - David Sancho
• Conventional dendritic cells exhibit tissue-specific characteristics that are regulated by mitochondrial metabolism - Stefanie K Wculek
• O-GlcNAcylation regulates dendritic cell transcriptional stability - Jose A Villadangos
• IL-21 as a central driver of immunosenescence: linking pulmonary dysfunction and neurodegeneration - Anshu AGRAWAL
• Dying cell-derived polyamines modulate dendritic cell phagocytosis and adaptive priming   - Chang Y Moon
• Aryl Hydrocarbon Receptor Inhibition Activates Mito-calcium/mtROS/IL-12 Axis in Dendritic Cells to Promote Tumor Suppression - Mridula Prakash Menon

Presentations are followed by reflections on Ralph's training and mentorship legacy from:

• Bei Wang
• Diana Dudziak
• Shannon Turley
• Björn Clausen
• Juliana Idoyaga
• Shinichiro Fuji

• The early days of dendritic cells - Jacques Banchereau
• Title Coming Soon - Ira Mellman
• Ralph Steinman's legacy in dendritic cell targeting and the balance between tolerance and protective immunity - Laura Bonifaz
• Transcription factor Etv3 controls the tolerogenic function of dendritic cells - Nicholas M Adams